HiRIS

Sources

The database contains 3,260 in vivo and 57,069 in vitro observations across 11,029 genes from the following sources.

Data source	First author	Publication	n
NCI-RID	Maldarelli F	HIV latency. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells.	2,160
NCI-RID	Ikeda T	Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy.	461
NCI-RID	Han Y	Resting CD4+ T cells from human immunodeficiency virus type 1 (HIV-1)-infected individuals carry integrated HIV-1 genomes within actively transcribed host genes.	74
NCI-RID	Mack KD	HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression.	34
Wagner-2014-Science	Wagner TA	HIV latency. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection.	531

Data source	First author	Publication	n
NCI-RID	Mack KD	HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression.	3
SherrillMix-2013	Pace MJ	Directly infected resting CD4+T cells can produce HIV Gag without spreading infection in a model of HIV latency.	5,603
SherrillMix-2013	Sherrill-Mix S	HIV latency and integration site placement in five cell-based models.	5,004
SherrillMix-2013	Lewinski MK	Genome-wide analysis of chromosomal features repressing human immunodeficiency virus transcription.	1,105
SherrillMix-2013	Shan L	Influence of host gene transcription level and orientation on HIV-1 latency in a primary-cell model.	719
Sunshine-2016-JVI	Sunshine S	HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay.	432
Wang-2007	Wang GP	HIV integration site selection: analysis by massively parallel pyrosequencing reveals association with epigenetic modifications.	44,203